The presence of high amounts of creatinine in the blood signals a damaged kidney

High Creatinine Levels: Causes, Symptoms And Treatment

October 1, 2020

The muscle tissues commonly use creatine for its energy source and creatinine is the waste byproduct of this process. This waste compound travels in the blood. When it reached the kidneys, it will then filter the blood and eventually flushed out creatinine from the body in the urine.

The kidneys regulate creatinine in the blood and maintain its levels to a minimum. If a person is found to have high levels of creatinine in the blood, it’s a sign that either his kidneys aren’t working properly or has kidney disease.

A healthy adult male should have creatinine levels in the blood within the ranges of 0.6 to 1.2mg/dL. Normal creatinine levels in the blood should be within the ranges of 0.5 to 1.1mg/dL for adult females.




Chronic Kidney Disease

The presence of high amounts of creatinine in the blood signals a damaged kidney. Medical practitioners use the glomerular filtration rate to measure creatine levels in the blood and make a diagnosis basing on test results. Blood creatinine level in the blood is normal if calculations result in a GFR of 60 or over. A GFR of lower than 60 signifies a kidney not functioning properly. A score of 15 or less may indicate kidney failure.

Intense physical workout

Creatine is one of the energy sources of muscles during physical workouts. Excessive workout enables our body to use more creatine and eventually increases creatinine levels.

Severe dehydration

Dehydration or insufficient presence of water in the body may cause injury to the kidneys. Thus, a damaged kidney will result in a higher amount of creatinine in the blood.


This medical condition refers to the blockage of the normal flow of urine. It impairs the kidneys’ ability to function properly and eventually causing damage, which increases creatinine in the blood. Examples of kidney obstruction are kidney stones and prostate enlargement.

Excess protein consumption

Meat-based products and foods rich in protein are found to increase creatine if consumed in excess of the daily recommended allowance. This also includes dietary supplements with high amounts of protein.


Certain medications like cimetidine and trimethoprim can increase creatinine for a temporary period.


High Creatinine Symptoms

Someone with a significant amount of creatinine in his blood may not be aware of it until a routine physical examination is performed. Symptoms of a high creatinine are caused by an existing medical condition that affects the function of the kidneys.


Some of the possible causes of a high creatinine level may involve one of the following:

  • Chest pains
  • Headache
  • Weight loss
  • Loss of appetite
  • Muscle ache
  • Hypertension (high blood pressure)
  • Frequent feelings of tiredness (fatigue)
  • Nausea
  • Vomiting
  • Swelling of the feet and hands
  • Pain sensation during urination
  • Unusual change in urine color



A high amount of creatinine in the blood can be detected through blood tests during your routine physical examinations. If the doctor observed high levels of creatinine, he may order another test because there are other factors that may temporarily increase your creatinine. This includes certain medications, foods, and dietary supplements with high protein compounds. And if multiple tests result in high amounts of creatinine in the blood, it may indicate an injured kidney.

The general condition of the kidneys can be evaluated by measuring the amount of creatinine that was filtered and the filtration rate estimations. This test is known as the Glomerular Filtration Rate and it’s performed in two methods. The first one is measured by using a certain formula that involves a persons’ age, weight, and blood creatinine level. The formula is 140 minus the persons’ age times weight (kg), and then divided by 72 times the blood creatinine level (mg/dL). The other method is conducted through a 24-hour evaluation of the collected a serum and urine sample. It’s performed by comparing creatinine levels found in both in the blood and urine. A healthy adult woman should have a creatinine filtration rate of 88-128 mL/min. For males, the creatinine level should be in the ranges of 97-137 mL/min.

Another test used to measure creatinine is called blood urea nitrogen (BUN). Urea is a metabolic byproduct that can also be an indicator of an improperly functioning kidney.

Infants may also develop abnormal blood creatinine levels, which may indicate the presence of a type of bacteremia. For adult males, a significantly high creatinine in the bloodstream may signify a prostate cancer.


Lower Your Creatinine Naturally

People with high levels of creatinine in their blood must work closely with their doctor. This is to identify what’s causing the creatinine levels to rise and for the doctor to provide appropriate treatment for the persons’ condition. There are also ways to naturally lower creatinine levels, it includes the following:


Increase intake of foods high in fiber

Dietary fibers are especially known to support the digestive system but it may also help the kidneys to filter out creatinine from the body.

One specific review published in the “European Journal of Clinical Nutrition” stated that fiber-rich foods may reduce blood creatinine levels. Even though many experts requested for further research, the initial study itself is believed to be strong enough to conclude that dietary fibers have a significant effect on decreasing creatinine in the blood. Also, increasing your dietary fiber is perfectly safe and immensely beneficial to your health. Examples of high fiber foods include leafy vegetables, fruits, whole grains, and seeds.


Raise your water intake

You can help your kidney not only flush out creatinine but also other harmful toxins just by improving your daily water intake. You may also add a slice of cucumber, lemon, or any citric fruits to make your drink more enjoyable. Green teas and herbal teas may also help eliminate waste and harmful toxins in your body.


Limit protein intake

One of the main causes of a high creatinine compound in the blood is excess protein consumption.

Cooked red meat, in particular, is found by some studies to cause a higher risk of increased creatinine than other food sources. This claim may be true if red meat is eaten in excess and still considered healthy if eaten in moderation.


Refrain from using creatine-rich supplements

Athletes and people with an active lifestyle commonly use certain supplements to boost their performance. These supplements, however, are usually high in creatine. Individuals with high levels of creatinine are advised to avoid supplements with creatine and seek medical counsel.


High Creatinine Levels Causes, Symptoms And Treatment